Stub1 chip
WebFull gene name according to HGNC. STIP1 homology and U-box containing protein 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. STUB1 (CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Read more.
Stub1 chip
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WebSTUB1/CHIP Antibody (A301-572A) in WB Detection of human and mouse STUB1/CHIP by western blot (h&m) and immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded), 293T … WebSep 24, 2024 · The ubiquitin ligase CHIP (C-terminus of Hsc70-interacting protein) is encoded by STUB1 and promotes ubiquitination of misfolded and damaged proteins. CHIP deficiency has been linked to several diseases, and mutations in the human STUB1 gene are associated with recessive and dominant forms of spinocerebellar ataxias (SCAR16/SCA48).
WebMar 21, 2024 · STUB1 (STIP1 Homology And U-Box Containing Protein 1) is a Protein Coding gene. Diseases associated with STUB1 include Spinocerebellar Ataxia, Autosomal … WebSTUB1 encodes for the protein C-terminus of Hsc70 Interacting Protein (CHIP), an E3 ubiquitin ligase. CHIP is known to regulate proteostasis by recruiting chaperones via a N-terminal… Show more
WebSTUB1, also named as CHIP, SDCCAG7, UBOX1 and NY-CO-7, is a E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. STUB1/CHIP modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It mediates transfer of non-canonical short ubiquitin chains to HSPA8 … WebOct 25, 2005 · Antibodies against STUB1 are found in patients with chronic lymphocytic leukemia (CLL) and in colorectal cancer patients. Catalytic activity S-ubiquitinyl- [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl- [acceptor protein]-L-lysine. 3 publications
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WebSTIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase Synonyms: CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1 Species: Human STUB1 (10273), Mouse Stub1 (56424), Rat Stub1 (287155), Zebrafish... Summary: STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in... Related Products: bucks county intermediate unit doylestownWebDetects human carboxyl terminus of hsc70-interacting protein (CHIP).Detects a band of approximately 35 kDa representing CHIP from COS-1 cells overexpressing the human … creek obh-21 buyWebSee all STUB1/CHIP primary antibodies Description Rabbit monoclonal [EPR4448] to STUB1/CHIP Host species Rabbit Tested applications Suitable for: WB, ICC/IF more details Unsuitable for: Flow Cyt or IHC-P Species … creek occupational therapyWebSTIP1 Homology and U-box Containing Protein 1 (STUB1), also known as Carboxyl Terminus of Hsp70-interacting Protein (CHIP), is a cytoplasmic protein that functions as a U-box Ubiquitin ligase (E3) (1). It is highly expressed in striated muscle and brain and has been observed at lower levels in other organs including the pancreas, lung, liver ... creeko.comWebThe carboxy terminus of Hsc70-interacting protein (CHIP, STUB1) is a co-chaperone protein and functional E3 ubiquitin ligase that links the polypeptide binding activity of Hsp70 to … creek obh-8seWebNov 16, 2024 · STUB1 disassociates AR/AR-V7 from HSP70, leading to AR/AR-V7 ubiquitination and degradation. ... The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins. Nat. Cell ... creek obh-8WebApr 4, 2024 · STUB1 is an intracellular checkpoint for interferon gamma sensing. STUB1-SMYD2 Axis Regulates Drug Resistance in Glioma cells. Regulation of STUB1 expression … creek ocean construction